When the sailors of Columbus returned from the new world they brought with them a disease of an unknown character, which speedily found its way into every part of Europe. None were exempt; the king on his throne, the beggar in his hovel, noble and peasant, priest and layman alike succumbed to the dire influence which made Christendom one vast charnel house.

Of it, Montesquieu said: “It is now two centuries since a disease unknown to our ancestors was first transplanted from the new world to ours, and came to attack human nature in the very source of life and pleasure. Most of the powerful families of the South of Europe were seen to perish by a distemper that was grown too common to be ignominious, and was considered in no other light than that of being fatal. Works, I, 265.